Sweaty Armpits


Underarm excessive sweating, also called axillary hyperhidrosis, is an uncontrollable, annoying, embarrassing, and isolating problem (to say the least). From the discomfort of sweat running down your sides, to the embarrassment of obvious sweat stains, to the fear of being "discovered," uncontrollable underarm sweating can feel like it's ruining your life.

But, there is good news:

Safe treatments for excessive sweating are available, the treatments work, and you have a number of options to choose from--or combine.


The first line of defense against excessive underarm sweating is antiperspirants. Antiperspirants are non-invasive, topical (applied on top of your skin), and available in a number of different strengths including "regular" over-the-counter products, "clinical strength" over-the-counter products, and perhaps even prescription antiperspirants. Most physicians recommend that you start with the mildest formulations ("regular" over-the-counter products), and if they don't give enough symptom relief, work your way up to the stronger clinical strength formulations and then, perhaps prescription antiperspirants. The recent advent of clinical strength antiperspirants has been shown to provide the same level of sweat management as prescription products, but with much less irritation. We are glad to see these new, and greatly improved, formulations on the drugstore shelves and easily available to everyone.

How you use antiperspirants is also incredibly important. Check out our information available about this, but the most important take-aways are: 1. apply antiperspirants before bed and 2. apply to totally dry skin to avoid irritation.

A wonderful addition to the wardrobe of anyone with underarm sweating (excessive or not!) is absorbent undershirts, absorbent tee shirts, absorbent dress shirts, and absorbent underarm pads.  You can nab a sweet coupon for them in our Fan Faves page -- note that our Fan Faves page is also a great place to learn about different antiperspirants available from companies who support our work and who understand Hh. 


Another treatment option, miraDry, is a different approach to eliminating axillary hyperhidrosis (underarm excessive sweating) and was cleared by the US FDA in January 2011. Clinical data from two study sites affiliated with the University of British Columbia showed miraDry successful in reducing underarm sweat in over 90% of patients through the final study visit that was 12 months after treatment. The average sweat reduction was 82%. And, patients rated their satisfaction with the treatment at 90%. While miraDry is promising for those who suffer from underarm sweating, it cannot be used to treat excessive sweating in any other area. Read the research findings, and understand the procedure for miraDry here.


If antiperspirants don't give you the relief you need and miraDry is not in your budget, your next option may be Botox (also known as onabotulinumtoxinA). An experienced medical professional can inject Botox into your underarms to dramatically reduce sweating. In one clinical study involving 322 patients with severe underarm sweating, 81% of the patients receiving injections achieved more than 50% reduction in sweating. And, 50% of the patients had their excessive sweating relieved for at least 201 days (nearly 7 months). Some, for over a year.

The use of miraDry and Botox for the treatment of hyperhidrosis is most effective when performed by a physician who has received special training and who has experience with the procedure. To find a physician in your area who is familiar with hyperhidrosis treatments, use our Clinician Finder and search for those who have the notation 'IHhS-Educated'.


As of June 2018, there is a new treatment option for hyperhidrosis of the underarms. Qbrexza (pronounced kew brex' zah) became available in October 2018. It comes in individually packaged cloths or wipes that can be used at home once per day to reduce underarm sweating. One wipe is intended to be used for two underarms. The treatment works by blocking receptors responsible for sweat gland activation. The active ingredient in Qbrexza is glycopyrronium tosylate, an anticholinergic formulation. In research studies of Qbrexza, the most common side effects were:

  • Dry mouth (in 16.9-24.2% of patients)
  • Erythema/area redness (in 17% of patients)
  • Burning/stinging (in 14.1% of patients)

Qbrexza was shown in clinical trials to improve sweating symptoms as soon as 1 week after starting the regimen. Studies also found that patients using Qbrexza wipes once daily for four weeks improved their “sweating severity” by nearly 25% to 30% (compared with 4% to 5% with placebo) and that measured sweat volume was reduced by 50% or more (in most patients.) The wipes were well-tolerated, and any reported side effects were primarily mild to moderate (see above). Qbrexza is FDA-approved for patients who are 9 years or older. Talk to your healthcare provider about whether Qbrexza might be a good choice for you, or not.


While many people find that antiperspirants, Botox injections, miraDry, or a combination of these hyperhidrosis treatments (or these treatments combined with an oral medication) are enough to manage even the most severe case of excessive sweating in the underarms, there are those who seek a surgical approach to treat their axillary hyperhidrosis. LOCAL underarm surgery techniques include excision, curettage, liposuction, and laser. During excision, sweat glands may be cut out. Similarly, during curettage, they may be scraped out. During liposuction, they may be removed by suction. Using lasers, tissue containing sweat glands is liquefied. Combinations of curettage and central excision, or of curettage and liposuction may be used, as well as combinations of liposuction and laser treatments. Dermatologists often have good results with these techniques. Each of these procedures can be done under local anesthesia (meaning that the patient is not completely "out"), and in an office setting (as opposed to in a hospital setting). To learn more about these local surgical options for axillary (underarm) hyperhidrosis, click here.

Please note that, in most cases, we do not recommend endoscopic thoracic sympathectomy (ETS) for excessive underarm sweating. While ETS is perhaps the most commonly discussed (as well as criticized) surgery for hyperhidrosis, there are other, far less risky, and far more predictable, options for people who suffer from excessive sweating of the underarms.

We hope that you'll find the information on this site helpful as you search for the best way to manage your underarm sweating problem. For updates about new research, the latest treatments, free treatment clinics, and daily management tips, be sure to sign-up to receive our free News Blog. We also have an extensive library of hyperhidrosis articles from peer-reviewed medical journals, so you can see where we get our facts and can share reliable medical data with your healthcare provider.