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Oral Medications



oral medication for excessive sweating Oral or systemic prescription medications are sometimes considered by physicians for the treatment of hyperhidrosis. Some of the medications that have been tried are anticholinergics, beta blockers, and clonidine hydrochloride (specific drug names include Propantheline, Glycopyrronium bromide, Benztropine, Diazepam, Diltiazem, Indomethacin, Oxybutynin, and Glycopyrrolate/Robinul.) Theoretically, these medicines could help treat excessive sweating because they prevent the stimulation of all sweat glands and thus may limit overall sweating, but long-term use is not recommended because of serious side effects. In fact, many physicians are not convinced that systemic anticholinergic drugs and other oral medications are appropriate for the treatment of primary focal hyperhidrosis (excessive sweating that is not linked to another medical condition and is localized to the hands, feet, face, and/or underarms).

How to Use Anticholinergics Effectively


As mentioned above, many experts do not think that anticholinergics or other oral medications have long-term usefulness for the treatment of excessive sweating that’s localized to the hands, feet, underarms, and/or face. This is because the drugs frequently have serious side effects such as:
  • Dry mouth
  • Blurred vision
  • Impaired speech, taste, chewing, and swallowing
  • Urinary retention
  • Constipation
  • Heart Palpitations

  • There is one promising use for anticholinergics, however. Some physicians and their patients have had great success treating sweaty palms and sweaty feet by adding a crushed anticholinergic tablet to the water used during iontophoresis. Learn more about iontophoresis and how anticholinergics can make the process even more effective.

    Next Steps


    Have you talked to your doctor about excessive sweating? If not, now is the time! Learn more about how you and your doctor can work together to find the right treatment, or combination of treatments, to manage your hyperhidrosis.

    If you’re considering an oral medication to treat excessive sweating, please know that experts in the field recommend that you try antiperspirants, iontophoresis, or Botox injections first. Click on the links provided to learn more about the usefulness of these treatments.

    And remember, because hyperhidrosis is a serious medical condition - you deserve insurance coverage and reimbursement for your doctor’s visits and treatments! We’ve got tips to help you navigate the health insurance realm and receive coverage.
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