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Botulinum Toxin Injections (Botox®): Botulinum Toxin A and Treatment of Hyperhidrosis
Botulinum toxin A injection has been used successfully to reduce excessive
sweating in all of the body areas affected in primary hyperhidrosis: axillary,
palmoplantar, and facial/gustatory. Characterized as a minimally invasive
treatment option compared to local surgery and endoscopic thoracic sympathectomy,
the use of botulinum toxin has become an important treatment option for patients not
responding to more-conservative therapies.[99]
Botulinum toxin A has been approved for use in hyperhidrosis in Canada, the U.K. and
other countries in Europe and South America (more than 23 countries total). In 2004,
the US Food and Drug Administration (FDA) approved botulinum toxin type A for the
treatment of severe primary axillary hyperhidrosis in patients unable to obtain
relief using antiperspirants.
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